I've actually tried it in SAI back in the day, but I remember that it was quite a hassle because I wasn't used to the pen tool there at all :') HOWEVER! Adobe has released CS2, for free, and it's exactly the same pixel art-wise. Bug-free as well, as I was worried it wasn't legit when I heard about this. But it is, and it's great, because my photoshop cs5 crashed. Here's the link if you missed it - helpx.adobe.com/creative-suite… Good luck!
I know what you mean, I have tried to pixel with SAI and it just doesn't work the same! I'm downloading that right now, thanks! I can't believe they have all those programmes just there to download. Thanks again! :3